Quality assessment of gene selection in microarray data
نویسندگان
چکیده
منابع مشابه
Quality assessment of gene selection in microarray data
In microarray data, gene selection can make data analysis efficient and biological interpretations of the selected genes can be very useful. However, microarray data has typically several thousands of genes but only tens of samples, referred to as a small sample size problem. In this paper, we discuss some problems on gene selection which can occur due to a small sample size: whether gene selec...
متن کاملGene Identification from Microarray Data for Diagnosis of Acute Myeloid and Lymphoblastic Leukemia Using a Sparse Gene Selection Method
Background: Microarray experiments can simultaneously determine the expression of thousands of genes. Identification of potential genes from microarray data for diagnosis of cancer is important. This study aimed to identify genes for the diagnosis of acute myeloid and lymphoblastic leukemia using a sparse feature selection method. Materials and Methods: In this descriptive study, the expressio...
متن کاملFeature Selection and Classification of Microarray Gene Expression Data of Ovarian Carcinoma Patients using Weighted Voting Support Vector Machine
We can reach by DNA microarray gene expression to such wealth of information with thousands of variables (genes). Analysis of this information can show genetic reasons of disease and tumor differences. In this study we try to reduce high-dimensional data by statistical method to select valuable genes with high impact as biomarkers and then classify ovarian tumor based on gene expression data of...
متن کاملQuality Assessment for Short Oligonucleotide Microarray Data
With the introduction of microarrays biologist have been witnessing entire labs shrinking to matchbox size. This paper invites quality researchers to join scientists on their fantastic journey into the world of microscopic high-throughput measurement technologies. Building a biological organism as laid out by the genetic code is a multi-step process with room for variation at each step. The fir...
متن کاملGene selection and ranking with microarray data
Over the past decade there has been an explosion in the amount of genomic data available to biomedical researchers due to advances in biotechnology. For example, using gene microarrays, it is now possible to probe a person’s gene expression profile over the more than 30,000 genes of the human genome. Signals extracted from gene microarray experiments can be linked to genetic factors underlying ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Optimization Methods and Software
سال: 2007
ISSN: 1055-6788,1029-4937
DOI: 10.1080/10556780600882082